1. What is Total Iron Binding Capacity?

Total Iron Binding Capacity (TIBC) is a medical laboratory test that measures the blood's capacity to bind iron with transferrin. It provides important information about iron metabolism and storage in the body.

2. How is TIBC Calculated?

TIBC is typically calculated using the formula:

Where:

• \( Transferrin \) — Serum transferrin level (mg/dL)
• \( 1.25 \) — Conversion factor

Note: In cases of laboratory error or insufficient data, TIBC calculation may not be possible.

3. Importance of TIBC Measurement

Details: TIBC measurement is crucial for diagnosing iron deficiency anemia, iron overload conditions, and monitoring various hematological disorders.

4. Using the Calculator

Tips: Enter transferrin level in mg/dL. The calculator will compute TIBC using the standard conversion formula. Valid transferrin values must be greater than 0.

5. Frequently Asked Questions (FAQ)

Q1: Why might TIBC be unable to calculate?
A: TIBC calculation requires accurate transferrin measurements. Laboratory errors, insufficient sample quality, or missing data can prevent calculation.

Q2: What are normal TIBC values?
A: Normal TIBC ranges from 250-450 μg/dL in adults, though reference ranges may vary by laboratory and population.

Q3: When is TIBC testing indicated?
A: TIBC is typically ordered when iron deficiency or iron overload is suspected, or as part of a comprehensive iron studies panel.

Q4: What factors affect TIBC levels?
A: TIBC levels can be affected by nutritional status, liver function, inflammation, and various medical conditions affecting iron metabolism.

Q5: How does TIBC relate to transferrin saturation?
A: Transferrin saturation is calculated as (Serum Iron ÷ TIBC) × 100%, providing important diagnostic information about iron availability.